Dr. Lin's  research  experience  spans  multiple  fields. He combined  the  fluorescence  spectroscopy  with  the  spectral  dynamics  to  study  the photophysical  properties  of  organic  light-emitting  diode  materials  and  excited-state  proton transfer molecules in graudate studies.  During  his  Ph.  D.  years  in  the University  of  Pennsylvania,   He used  the  time-resolved  infrared  spectroscopy  to  study  the  folding  mechanism  of  protein molecules.  He further expanded his research to the field  of  viral  protein and  successfully  resolved  the  conformational  dynamics  of influenza  A  M2  proton  channel  during  the  infection. In addition, Dr. Lin demonstrated his ability in theoretical modeling. He used one-dimensional Ising model to simplify  the  protein  system  to  simulate  the  folding  process  of  protein.  He successfully extracted the key folding information, the nucleation and propagation rate constants, in the field  of  protein  folding  using  the  previously  published  experimental  data. As a postdoctoral researcher, Dr. Lin again expanded his  research  to  cell biology.  Dr.  Lin  first  published  his  study  in  PNAS using nanopore material to introduce different proteins into cells and make the world’s first three-color single-molecule measurement interrogating the interaction among three different proteins  in  a  single  cell.  Dr.  Lin also  made  another  breakthrough  in  the  research  of epidermal  growth  factor  receptor  (EGFR).  EGFR  controls  the proliferation  of  cells.  It  is overexpressed  or  hyperactivated  due  to  the  mutations  in  several  types  of  cancer  cells, He showed that EGFR forms clusters with the downstream protein in the signaling pathway upon activation and undergoes protein  phase  transition  on  the  two-dimensional  lipid  membrane.